It should work fine, it is a 9.5mm drive height ...... the newest gen of this drive would be best with current firmware updates....... i might be wrong but remembered reading the 1st gen of these drives had some problems with OSX systems, i might be wrong just what i am recalling having read something awhile ago for OSX specific systems.
Another consideration is a Western Digital black 4k sector drive model ( more space after formatting)........ Also quite a bit less expensive. I use the WD black drives in all the laptops i fix, upgrade. A considerable performance upgrade from stock, and a 5 year warranty....... however as memory serves the 320GB is the largest of the 9.5mm height in this model line.
The Black line isn't going to stack up against a hybrid drive just offering an opinion about cost effective vs. performance and what i know to work well in several macs of all types i have used them in.
I also just wanted to answer the question as i didn't have time to look up several references i had read i mentioned above. I think OWC should have some detailed info about drive models and supported macs for these Seagate drives. Once you have the model info for the newest seagate drive, user reviews on various web sites, newegg etc...... often mention the computer the drive was used in and if any problems occurred.
Hope this helps.