Cannot change the Printer Settings

MacBook Pro (Retina 15-inch Mid 2014)... Stylus Pro 3880 with 9.33 driver Mac Sierra OS 10.12.6

I cannot change the Printer Settings. I have tried using Photoshop CS6, Lightroom 5, On One Photo Raw and Preview and it cannot be done in any of those programs. I have had Epsom and Apple try to solve the problem over the net but neither has cracked it. We have removed and added the printer and the Operating System a number of times as well as setting up a new user on the Mac. In addition all permissions have been reset.

When I click on the print settings button I get the dialogue box pop up and I make all of the changes but when I click on the Save button nothing happens. In the end I have to cancel to close the dialogue box and no changes are saved. The printer appears to be working fine and communicates well with the computer. It prints ok with the current settings and I can view ink levels etc with no issue.

I am hoping that someone here has had this happen and can give me the answer.