35 minutes - 1 hour
I blew the screen out of a Ipod Nano 6 gen. I was going to throw it away then found the Ifixit repair article.
It couldn't have been any easier. The ifixit article walked me through replacing the screen, and in all it took about 20 minutes.
Don't hesitate. Ifixit was a one-stop repair shop.
Phillips #00 Screwdriver
iFixit Opening Tool
iPod nano (6th Gen) Display Assembly