It's pretty tedious. You can remove the front and back panels with minimal technical difficulties. The trouble will be removing the ribbon cables, buttons and the rest of the innards without damaging anything. The ribbon cables are extremely delicate. I ripped one while removing the cable that connects to the power button. This phone is far more complicated that the 3G or 3GS. The components are much harder to remove much less put back into place.
With all that being said, it can be done if you devote plenty of time to the project. You'll also need to be extremely careful while working to remove the ribbon cables. Placing the components back into the new frame will take patience.