I don't know if this will help, but:

1.) Plug it into your computer when you try to work on it. But leave it plugged in for around an hour before you try to work on it, just in case the battery is so low that it neeeds to charge itself before it will even acknowledge a command.

2.) Make sure the hold button (however you do this on an iPod Touch, I'm not sure.) is off.

3.) When the iPod has had a chance to recharge a bit, try to turn it on again. I don't know how to do a force-reset on an iPod Touch (on mine it is hold down center key + menu for a few seconds) but that may very well fix your problem if you know how to do a force reset.

4.) Does iTunes acknowledge the iPod? at an extreme, if none of these work, you may have to restore your iPod to factory defaults. Just remember that doing that would wipe out everything on your iPod.

This link may also help.

http://support.apple.com/manuals/#ipod