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Current version by mayer,

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Spray a little Windex on a very soft cloth and see if it will dissolve.
Update: If the speck bothers you that much, here's the guide for replacing the screen: http://www.ifixit.com/Guide/Repair/Repairing-MacBook-Core-2-Duo-Installing-LCD-Inverter-fast-method-A1181/3631/1

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Edit by mayer,

Text:

SraySpray a little Windex on a very soft cloth and see if it will dissolve.
SraySpray a little Windex on a very soft cloth and see if it will dissolve.

Status:

open

Original post by mayer,

Text:

Sray a little Windex on a very soft cloth and see if it will dissolve.

Status:

open